First News

Blood Pressure Drug May Slow Diabetes Progression

The scientists were doing experiments with mouses. They thinks that obstruction in the duct of calcium, can is causes of two main illness. Also they were find in the last clinical proves, that the medicine called “Verapamilo” can postpone the Diabetes. Beta cells secrete insulin to control blood sugar levels, but begin to die as patients develop Type 1 or Type 2 diabetes. So far anybody had noticed that because of the obtruccions in the ducts of calcium, betas cells die. Recent studies also have suggested that lowering TXNIP levels in the heart lessens the damage caused by a heart attack.

The team of the UAB will join with Southern Research Institute and the Alabama Drug Discovery Alliance, for double people. People that help discover more experiments about people with Diabetes.

PROVES:

In diabetic, verapamil treatment maintained normal glucose level, while glucose spiked in control mice. This was accompanied by an 80 percent reduction in TXNIP levels in isolated islets of verapamil-treated animals. . The results also suggest that the drug can stop diabetes in mice with longstanding disease and is most effective when given early. "The debate now should begin as to whether physicians should consider verapamil an additional treatment to protect beta cells in patients with both hypertension and diabetes”.

Analysis of the INVEST trial revealed that newly diagnosed diabetes was less common in patients treated with verapamil, especially in the Hispanic population.